Official Full Name
Homo sapiens signal-regulatory protein beta 1 DNA.
The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene.
SIRPB1; signal-regulatory protein beta 1; signal-regulatory protein beta-1; CD172b; SIRP BETA 1; CD172 antigen like family member B; CD172b antigen; DKFZp686A05192; Signal regulatory protein beta 1; SIRP beta 1 isoform 3; OTTHUMP00000029992; OTTHUMP00000029993; OTTHUMP00000029994; CD172 antigen-like family member B; SIRP-BETA-1; FLJ26614; RP4-576H24.1