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siah2

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Official Full Name
siah E3 ubiquitin protein ligase 2
Background
This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia. [provided by RefSeq, Jul 2008]
Synonyms
SIAH2; siah E3 ubiquitin protein ligase 2; hSiah2; E3 ubiquitin-protein ligase SIAH2; siah-2; seven in absentia homolog 2