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sh3bp4

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Official Full Name
SH3-domain binding protein 4
Background
This gene encodes a protein with 3 Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. This protein is involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of a specific protein receptor.
Synonyms
SH3BP4; SH3-domain binding protein 4; SH3 domain-binding protein 4; EH-binding protein 10; transferrin receptor trafficking protein; transferrin receptor-trafficking protein; TTP; BOG25; TTP, BOG25; si:dkey-57b6.3