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sftpa1

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Official Full Name
surfactant protein A1
Background
This gene encodes a lung surfactant protein that is a member of a subfamily of C-type lectins called collectins. The;encoded protein binds specific carbohydrate moieties found on lipids and on the surface of microorganisms. This;protein plays an essential role in surfactant homeostasis and in the defense against respiratory pathogens. Mutations;in this gene are associated with idiopathic pulmonary fibrosis. Alternate splicing results in multiple transcript;variants.
Synonyms
SFTPA1; SPA; PSAP; PSPA; SP-A; SPA1; PSP-A; SFTP1; SP-A1; COLEC4; SFTPA1B; pulmonary surfactant-associated protein A1; collectin-4; surfactant protein A1B; alveolar proteinosis protein; surfactant protein A1 variant AD' 6A; surfactant protein A1 variant AD' 6A2; surfactant protein A1 variant AD' 6A3; surfactant protein A1 variant AD' 6A4; surfactant protein A1 variant ACD' 6A2; surfactant protein A1 variant ACD' 6A3; surfactant protein A1 variant ACD' 6A4; surfactant protein A1 variant AB'D' 6A2; surfactant protein A1 variant AB'D' 6A3; surfactant protein A1 variant AB'D' 6A4; surfactant, pulmonary-associated protein A1A; surfactant, pulmonary-associated protein A1B; 35 kDa pulmonary surfactant-associated protein