Official Full Name
serine/arginine-rich splicing factor 5
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein have been found for this gene.
HRS; SFRS5; SRP40; serine/arginine-rich splicing factor 5; SR splicing factor 5; delayed-early protein HRS; pre-mRNA-splicing factor SRP40; splicing factor, arginine/serine-rich 5; SRSF5