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sf3b4

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Official Full Name
splicing factor 3b, subunit 4, 49kDa
Background
This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
Synonyms
SF3B4; splicing factor 3b, subunit 4, 49kDa; splicing factor 3b, subunit 4, 49kD; splicing factor 3B subunit 4; Hsh49; SAP49; SF3b49; MGC10828; Pre mRNA splicing factor SF3b 49 kDa subunit; SAP 49; SF3b50; Spliceosomal protein; Spliceosome associated protein (U2 snRNP); Spliceosome associated protein 49; Spliceosome-associated protein (U2 snRNP); Splicing factor 3b subunit 4 49kDa; spliceosome-associated protein 49; pre-mRNA splicing factor SF3b 49 kDa subunit; pre-mRNA-splicing factor SF3b 49 kDa subunit; splicing factor 3b, subunit 4; fb36a04; chunp6902; wu:fb36a04