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sf3a3

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Official Full Name
splicing factor 3a, subunit 3, 60kDa
Background
This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20.
Synonyms
SF3A3; splicing factor 3a, subunit 3, 60kDa; splicing factor 3a, subunit 3, 60kD; splicing factor 3A subunit 3; PRP9; PRPF9; SAP61; SF3a60; Pre mRNA splicing factor SF3a (60kD); Pre mRNA splicing factor SF3a; PRP 9; PRPF 9; SAP 61; Spliceosome associated protein 61; Splicing factor 3a subunit 3 60kDa; OTTHUMP00000004730; spliceosome-associated protein 61; pre-mRNA splicing factor SF3a (60kD); splicing factor 3a, subunit 3; wu:fi15a06; wu:fj94f01; zgc:110227

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