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selm

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Official Full Name
selenoprotein M
Background
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3 UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This gene is expressed in a variety of tissues, and the protein is localized to the perinuclear structures.
Synonyms
SELM; selenoprotein M; SelM protein; SEPM; OTTHUMP00000199395; OTTHUMP00000199396; selenoprotein SelM; MGC40146; cb693; wu:fc13f12; zgc:103431; fc13f12