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sdc2

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Official Full Name
syndecan 2
Background
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008]
Synonyms
SDC2; syndecan 2; HSPG; CD362; HSPG1; SYND2; syndecan-2; fibroglycan; syndecan proteoglycan 2; heparan sulfate proteoglycan core protein; cell surface-associated heparan sulfate proteoglycan 1; heparan sulfate proteoglycan 1, cell surface-associated; heparan sulfate proteoglycan 1, cell surface associated , HSPG, HSPG1; syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan); cb440; zgc:103676

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