Official Full Name
SCY1-like 1 (S. cerevisiae)
This gene encodes a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. It activates transcription of the telomerase reverse transcriptase and DNA polymerase beta genes. The protein has been localized to the nucleus, and also to the cytoplasm and centrosomes during mitosis. Multiple transcript variants encoding different isoforms have been found for this gene.
SCYL1; SCY1-like 1 (S. cerevisiae); N terminal kinase like , NTKL; N-terminal kinase-like protein; GKLP; HT019; MGC78454; NKTL; P105; TAPK; TEIF; telomerase regulation associated protein; telomerase transcriptional elements interacting factor; teratoma associated tyrosine kinase; TRAP; Coated vesicle associated kinase of 90 kDa; CVAK90; Likely ortholog of mouse N terminal kinase like protein; N terminal kinase like; N terminal kinase like protein; NTKL; NTKLBP1; SCY L1; SCY1 like 1; SCY1 like 1 protein 1; SCYL 1; SCYL1BP1; Telomerase transcriptional element interacting factor; SCY1-like protein 1; teratoma-associated tyrosine kinase; telomerase regulation-associated protein; coated vesicle-associated kinase of 90 kDa; telomerase transcriptional element-interacting factor; telomerase transcriptional ele; telomerase transcriptional elements-interacting factor; likely ortholog of mouse N-terminal kinase-like protein