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scarf1

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Official Full Name
scavenger receptor class F, member 1
Background
The protein encoded by this gene is a scavenger receptor that is expressed in endothelial cells and mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Transcription factors ZNF444/EZF-2 and SP1 are found to be responsible for the regulation of this gene. Five alternatively spliced transcript variants encoding distinct isoforms have been described.
Synonyms
SCARF1; scavenger receptor class F, member 1; scavenger receptor class F member 1; acetyl LDL receptor; KIAA0149; scavenger receptor expressed by endothelial cells; SREC; endothelial cells scavenger receptor; scavenger receptor expressed by endothelial ce