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satb2

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Official Full Name
SATB homeobox 2
Background
This gene encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. The encoded protein is involved in transcription regulation and chromatin remodeling. Defects in this gene are associated with isolated cleft palate and mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein.
Synonyms
SATB2; SATB homeobox 2; SATB family member 2; DNA-binding protein SATB2; FLJ21474; KIAA1034; special AT-rich sequence-binding protein 2; FLJ32076; MGC119474; MGC119477; special AT-rich sequence binding protein; si:ch211-223c6.1; AT-rich sequence binding protein 2; special AT-rich sequence binding protein 2