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sat1

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Official Full Name
spermidine/spermine N1-acetyltransferase 1
Background
The protein encoded by this gene belongs to the acetyltransferase family, and is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. It catalyzes the acetylation of spermidine and spermine, and is involved in the regulation of the intracellular concentration of polyamines and their transport out of cells. Defects in this gene are associated with keratosis follicularis spinulosa decalvans (KFSD). Alternatively spliced transcripts have been found for this gene.
Synonyms
SAT1; spermidine/spermine N1-acetyltransferase 1; diamine acetyltransferase 1; DC21; EC 2.3.1.57; KFSD; Polyamine N acetyltransferase 1; Polyamine N-acetyltransferase 1; Putrescine acetyltransferase; SAT; SAT1_HUMAN; Spermidine/spermine N(1) acetyltransferase 1; Spermidine/spermine N(1)-acetyltransferase 1; SSAT 1; SSAT; SSAT-1; SAT, spermidine/spermine N1 acetyltransferase; diamine N acetyltransferase 1; diamine N-acetyltransferase 1; spermidine/spermine N1-acetyltransferase alpha; KFSDX