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sart3

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Official Full Name
squamous cell carcinoma antigen recognized by T cells 3
Background
The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing.
Synonyms
SART3; squamous cell carcinoma antigen recognized; squamous cell carcinoma antigen recognised by T cells 3; squamous cell carcinoma antigen recognized by T-cells 3; KIAA0156; RP11 13G14; hSART 3; p110(nrb); RP11-13G14; Tat interacting protein of 110 kDa; TIP110; SART-3; hSART-3; tat-interacting protein of 110 kDa; P100; p110; DSAP1; squamous cell carcinoma antigen recognized by T cells 3; wu:fc51h03; zC191D15.4; si:ch211-191d15.4; egy; earl grey

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