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sae1

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Official Full Name
SUMO1 activating enzyme subunit 1
Background
The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
Synonyms
SAE1; SUMO1 activating enzyme subunit 1; SUMO-activating enzyme subunit 1; activator Of sumo 1; AOS1; FLJ3091; Sua1; activator of SUMO1; SUMO-1 activating enzyme subunit 1; sentrin/SUMO-activating protein AOS1; SUMO-1 activating enzyme E1 N subunit; ubiquitin-like 1-activating enzyme E1A; ubiquitin-like protein SUMO-1 activating enzyme; UBLE1A; HSPC140; AOS1, SUA1, UBLE1A, HSPC140; sae2a; zgc:86633; wu:fa28b04; fa28b04; SUMO1 activating enzyme subunit 2a; ubiquitin-like 1 (sentrin) activating enzyme E1A