Creative biogene
SHARE THIS
facebook twitterlinkedingoogle plusStumbleUpon blog


Products
CBpromise

24x7 CUSTOMER SERVICE

CONTACT US TO ORDER

;

rrm2b

Bookmark and Share
Official Full Name
ribonucleotide reductase M2 B (TP53 inducible)
Background
This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]
Synonyms
RRM2B; ribonucleotide reductase M2 B (TP53 inducible); P53R2; MTDPS8A; MTDPS8B; ribonucleoside-diphosphate reductase subunit M2 B; TP53-inducible ribonucleotide reductase M2 B; p53-inducible ribonucleotide reductase small subunit 2 homolog; p53-inducible ribonucleotide reductase small subunit 2-like protein; p53-inducible ribonucleotide reductase small subunit 2 short form beta; MGC42116; MGC102856; DKFZp686M05248; ribonucleotide reductase M2 b; rrm2; fb72h01; fb93b05; wu:fb72h01; wu:fb93b05; si:zc215i13.5

CONTACT CREATIVE BIOGENE

45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-biogene.com

Europe
Tel: 44-207-097-1828

Terms & Conditions | Privacy Policy | Sitemap | FAQ | © 2010-2018 Creative Biogene. All Rights Reserved.