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rptor

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Official Full Name
Homo sapiens regulatory associated protein of MTOR, complex 1 DNA.
Background
This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms
KOG1; Mip1; KIAA1303; regulatory-associated protein of mTOR; raptor; p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats; RPTOR; regulatory associated protein of MTOR, complex 1; KOG1, Mip1