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rnf6

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Official Full Name
ring finger protein (C3H2C3 type) 6
Background
The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.
Synonyms
RNF6; ring finger protein (C3H2C3 type) 6; E3 ubiquitin-protein ligase RNF6; DKFZp686P0776; RING H2 protein RNF 6; Ring finger protein 6; RING H2 protein; RING H2 protein RNF6; RNF 6; OTTHUMP00000018154; OTTHUMP00000018155; OTTHUMP00000018156; RING-H2 protein RNF-6