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rnf111

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Official Full Name
ring finger protein 111
Background
The protein encoded by this gene contains a RING finger domain, a motif known to be involved in protein-protein and protein-DNA interactions. The mouse counterpart of this gene (Rnf111/arkadia) has been shown to genetically interact with the transforming growth factor (TGF) beta-like factor Nodal, and act as a modulator of the nodal signaling cascade, which is essential for the induction of mesoderm during embryonic development.
Synonyms
RNF111; ring finger protein 111; E3 ubiquitin-protein ligase Arkadia; ARK; Arkadia; DKFZP761D081; FLJ38008; DKFZp313E0731; DKFZp686H1966; zmp:0000001195; RING finger E3 ubiquitin-protein ligase

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