This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein is an important signalling protein for sarcomere assembly and has been shown to play a significant role in the exocytosis of the solute carrier family 2, facilitated glucose transporter member 4 and other proteins, possibly acting as the signal that turns on the membrane fusion machinery. Three related pseudogene have been identified on chromosomes 2 and 14.
RHOQ; ras homolog gene family, member Q; ARHQ, RAS like, family 7, member A , RASL7A; rho-related GTP-binding protein RhoQ; TC10; ARHQ; Ras homolog gene family member Q; RAS like family 7 member A; Ras like protein family member 7A; Ras like protein TC10; Ras related GTP binding protein TC10; Ras-like protein family member 7A; Ras-like protein TC10; RASL7A; Rho related GTP binding protein RhoQ; RHOQ_HUMAN; TC10A; RAS-like, family 7, member A; ras homolog family member Q; ARHQ, ras homolog gene family, member Q , RAS like, family 7, member A , RASL7A; ARHQ, TC10, TC10A, RASL7A; CHTC10; Rho small GTPase TC10; zgc:55997; wu:fi15a09