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rgs17

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Official Full Name
regulator of G-protein signaling 17
Background
This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
Synonyms
RGS17; regulator of G-protein signaling 17; regulator of G protein signalling 17; RGS 17; RGSZ2; Regulator of G protein signalling Z2; RGS17_HUMAN; RGS-17; hRGS17; RGS protein RGS-17; regulator of G-protein signalling 17; zgc:92802

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