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rbm5

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Official Full Name
RNA binding motif protein 5
Background
This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer.
Synonyms
RBM5; RNA binding motif protein 5; RNA-binding protein 5; H37; LUCA15; putative tumor suppressor LUCA15; renal carcinoma antigen NY-REN-9; G15; RMB5; FLJ39876; wu:fc25a08; wu:fe06f12

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