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rbbp5

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Official Full Name
retinoblastoma binding protein 5
Background
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2010]
Synonyms
RBBP5; retinoblastoma binding protein 5; RBQ3; SWD1; retinoblastoma-binding protein 5; RBBP-5; retinoblastoma-binding protein RBQ-3; SWD1, Set1c WD40 repeat protein, homolog; Set1c WD40 repeat protein; homolog (S. cerevisiae); zgc:56078; zgc:85864

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