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Official Full Name
retina and anterior neural fold homeobox
Background
This gene encodes a homeobox-containing transcription factor that functions in eye development. The gene is expressed early in the eye primordia, and is required for retinal cell fate determination and also regulates stem cell proliferation. Mutations in this gene have been reported in patients with defects in ocular development, including microphthalmia, anophthalmia, and coloboma.
Synonyms
RAX; retina and anterior neural fold homeobox; retinal homeobox protein Rx; RX; retina and anterior neural fold homeobox protein; MCOP3; RX1; RX2; orx; cRax; cRax1; cRax2; retinal homeobox protein Rx1; retinal homeobox protein Rx2; orthodenticle-related homeobox protein