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rasal1

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Official Full Name
RAS protein activator like 1 (GAP1 like)
Background
The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate;the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the;protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS,;thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains;which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members,;this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants;that encode different isoforms have been described.
Synonyms
RASAL1; RAS protein activator like 1 (GAP1 like); rasGAP-activating-like protein 1; RASAL; GAP1 like protein; MRASAL; RAS GTPase activating protein like; rasGAP activating like protein 1; RASGAP1 LIKE; RASL1_HUMAN