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rad54l

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Official Full Name
RAD54-like (S. cerevisiae)
Background
The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.
Synonyms
RAD54L; RAD54-like (S. cerevisiae); RAD54 (S.cerevisiae) like; DNA repair and recombination protein RAD54-like; hHR54; hRAD54; RAD54A; RAD54 homolog; HR54; zgc:56289

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