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rabgef1

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Official Full Name
RAB guanine nucleotide exchange factor (GEF) 1
Background
RABGEF1 forms a complex with rabaptin-5 (RABPT5; MIM 603616) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor (GEF) for RAB5 (RAB5A; MIM 179512) (Horiuchi et al., 1997 [PubMed 9323142]).[supplied by OMIM, Mar 2010]
Synonyms
RABGEF1; RAB guanine nucleotide exchange factor (GEF) 1; RAP1; RABEX5; rabex-5; rab5 GDP/GTP exchange factor; rabaptin-5-associated exchange factor for Rab5; rabex 5; FLJ32302; zgc:65944

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