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rab3gap1

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Official Full Name
RAB3 GTPase activating protein subunit 1 (catalytic)
Background
This gene encodes the catalytic subunit of a Rab GTPase activating protein. The encoded protein forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. This protein mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in this gene are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants.
Synonyms
RAB3GAP1; RAB3 GTPase activating protein subunit 1 (catalytic); rab3 GTPase-activating protein catalytic subunit; KIAA0066; RAB3GAP; RAB3GAP130; WARBM1; rab3-GAP p130; RAB3 GTPase-activating protein 130 kDa subunit; P130; DKFZp434A012; RAB3 GTPase activating protein subunit 1; fj56a04; wu:fj56a04; zgc:152826

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