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ptprr

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Official Full Name
protein tyrosine phosphatase, receptor type, R
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12. [provided by RefSeq, May 2011]
Synonyms
PTPRR; protein tyrosine phosphatase, receptor type, R; PTPRQ; EC-PTP; PCPTP1; PTP-SL; PTPBR7; receptor-type tyrosine-protein phosphatase R; R-PTP-R; NC-PTPCOM1; ch-1PTPase; Ch-1 PTPase; protein-tyrosine phosphatase PCPTP1; protein tyrosine phosphatase Cr1PTPase; protein-tyrosine phosphatase NC-PTPCOM1; EC PTP; PTP SL; FLJ34328; MGC131968; MGC148170; DKFZp781C1038