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ptk7

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Official Full Name
protein tyrosine kinase 7
Background
Receptor protein tyrosine kinases transduce extracellular signals across the cell membrane. A subgroup of these kinases lack detectable catalytic tyrosine kinase activity but retain roles in signal transduction. The protein encoded by this gene is a member of this subgroup of tyrosine kinases and may function as a cell adhesion molecule. This gene is thought to be expressed in colon carcinomas but not in normal colon, and therefore may be a marker for or may be involved in tumor progression. Four transcript variants encoding four different isoforms have been found for this gene.
Synonyms
PTK7; PTK7 protein tyrosine kinase 7; inactive tyrosine-protein kinase 7; CCK4; CCK-4; colon carcinoma kinase 4; colon carcinoma kinase-4; protein-tyrosine kinase 7; tyrosine-protein kinase-like 7; pseudo tyrosine kinase receptor 7; protein tyrosine kinase 7; KLG; kinase-like protein