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ptgr2

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Official Full Name
prostaglandin reductase 2
Background
This gene encodes an enzyme involved in the metabolism of prostaglandins. The encoded protein catalyzes the NADPH-dependent conversion of 15-keto-prostaglandin E2 to 15-keto-13,14-dihydro-prostaglandin E2. This protein may also be involved in regulating activation of the peroxisome proliferator-activated receptor. Alternative splicing results in multiple transcript variants.
Synonyms
PTGR2; prostaglandin reductase 2; ZADH1, zinc binding alcohol dehydrogenase domain containing 1; FLJ39091; 15 oxoprostaglandin 13 reductase; 15 oxoprostaglandin delta 13 reductase; DKFZp686P10120; FLJ99229; PGR 2; PGR2; PTGR 2; Zinc binding alcohol dehydrogenase domain containing 1; Zinc binding alcohol dehydrogenase domain containing protein 1; PRG-2; 15-oxoprostaglandin 13-reductase; 15-oxoprostaglandin-delta13-reductase; zinc binding alcohol dehydrogenase, domain containing 1; zinc-binding alcohol dehydrogenase domain-containing protein 1; ZADH1; im:6903726; si:dkey-119a7.6