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psmd10

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Official Full Name
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
Background
This gene encodes a subunit of the PA700/19S complex, which is the regulatory component of the 26S proteasome. The 26S proteosome complex is required for ubiquitin-dependent protein degradation. This protein is a non-ATPase subunit that may be involved in protein-protein interactions. Aberrant expression of this gene may paly a role in tumorigenesis. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.
Synonyms
PSMD10; proteasome (prosome, macropain) 26S subunit, non-ATPase, 10; 26S proteasome non-ATPase regulatory subunit 10; gankyrin; p28; ankyrin repeat protein; 26S proteasome regulatory subunit p28; hepatocellular carcinoma-associated protein p28-II; p28(GAN; p28(GANK); dJ889N15.2; RP5-889N15.3, dJ889N15.2, p28, p28(GANK), PSMD10; zgc:109707; gank; proteasome 26S subunit, non-ATPase, 10