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psmb3

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Official Full Name
proteasome (prosome, macropain) subunit, beta type, 3
Background
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Pseudogenes have been identified on chromosomes 2 and 12.
Synonyms
PSMB3; proteasome (prosome, macropain) subunit, beta type, 3; proteasome subunit beta type-3; HC10 II; MGC4147; C10 II; DELTA; EC 3.4.25.1; LMPY; Macropain delta chain; Macropain subunit beta type 6; MGC5169; Multicatalytic endopeptidase complex delta chain; Prosome subunit beta type 6; proteasome (prosome, macropain) subunit, beta type 3; Proteasome beta 3 subunit; Proteasome chain 13; proteasome component C10 II; Proteasome delta chain; Proteasome subunit beta type 6; Proteasome subunit beta type 6 precursor; Proteasome subunit Y; Proteasome theta chain; PSMB6; proteasome component C10-II; HC10-II; zgc:56374; zgc:92596; wu:fb11d10; wu:fu88b08; macropain) subunit