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prss16

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Official Full Name
protease, serine, 16 (thymus)
Background
This gene encodes a serine protease expressed exclusively in the thymus. It is thought to play a role in the alternative antigen presenting pathway used by cortical thymic epithelial cells during the positive selection of T cells. The gene is found in the large histone gene cluster on chromosome 6, near the major histocompatibility complex (MHC) class I region. A second transcript variant has been described, but its full length nature has not been determined.
Synonyms
PRSS16; protease, serine, 16 (thymus); thymus-specific serine protease; TSSP; serine protease 16; thymus specific serine peptidase; FLJ36271; FLJ40714; FLJ44172; wu:fi04d10; wu:fi36c10; zgc:158605; uncharacterized protein LOC556307; protease, serine, 16 (thymus)-like