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prss1

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Official Full Name
protease, serine, 1 (trypsin 1)
Background
This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7.
Synonyms
PRSS1; protease, serine, 1 (trypsin 1); TRY1; trypsin-1; Alpha-trypsin chain 2; Beta-trypsin; Cationic trypsinogen; Serine protease 1; TRY1_HUMAN; Trypsin I; trypsinogen 1; trypsinogen A; digestive zymogen; nonfunctional trypsin 1; TRP1; TRY4; TRYP1; FLJ57296; MGC120175; MGC149362; DKFZp779A0837

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