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prpf4

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Official Full Name
pre-mRNA processing factor 4
Background
The protein encoded by this gene is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. The encoded protein also is a mitotic checkpoint protein and a regulator of chemoresistance in human ovarian cancer. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms
PRPF4; PRP4 pre-mRNA processing factor 4 homolog (yeast); U4/U6 small nuclear ribonucleoprotein Prp4; HPRP4; HPRP4P; PRP4; PRP4/STK/WD splicing factor; Prp4p; PRP4 homolog; WD splicing factor Prp4; U4/U6 snRNP 60 kDa protein; zgc:65943; mg:ab03a02

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