Tel: 1-631-626-9181 (USA)   44-207-097-1828 (Europe)

CBpromise   

Our promise to you:
Guaranteed product quality, expert customer support.

24x7 CUSTOMER SERVICE
CONTACT US TO ORDER

proz

Bookmark and Share
Official Full Name
protein Z, vitamin K-dependent plasma glycoprotein
Background
This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the;plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent;protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein;are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the;cause of protein Z deficiency. Alternate splicing results in multiple transcript variants.
Synonyms
PROZ; protein Z, vitamin K-dependent plasma glycoprotein; vitamin K-dependent protein Z; PZ; Protein Z, vitamin K dependent plasma glycoprotein; OTTHUMP00000018738; OTTHUMP00000018739