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prop1

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Official Full Name
PROP paired-like homeobox 1
Background
This gene encodes a paired-like homeodomain transcription factor in the developing pituitary gland. Expression occurs prior to and is required for expression of pou domain transcription factor 1, which is responsible for pituitary development and hormone expression. Mutations in this gene have been associated with combined pituitary hormone deficiency-2 as well as deficiencies in luteinizing hormone, follicle-stimulating hormone, growth hormone, prolactin, and thyroid-stimulating hormone.
Synonyms
PROP1; PROP paired-like homeobox 1; prophet of Pit1, paired like homeodomain transcription factor; homeobox protein prophet of Pit-1; Homeobox protein prophet of Pit 1; Pituitary specific homeodomain factor; PROP 1; PROP paired like homeobox 1; pituitary-specific homeodomain factor; prophet of Pit1, paired-like homeodomain transcription factor; CPHD2; PROP-1; si:ch211-93n23.5; paired-like homeodomain transcription factor prop1