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Official Full Name
protein C (inactivator of coagulation factors Va and VIIIa)
Background
Protein?C, also known as autoprothrombin IIA and blood coagulation factor XIV, is a zymogenic (inactive) protein, the activated form of which plays an important role in regulating blood clotting, inflammation, cell death and maintaining the permeability of blood vessel walls in humans and other animals. Activated protein?C (APC) performs these operations primarily by proteolytically inactivating proteins Factor Va and Factor VIIIa. APC is classified as a serine protease, as it contains a residue of serine in its active site. In humans, protein?C is encoded by the PROC gene, which is found on chromosome 2
Synonyms
PROC; PROC1; PC; APC; vitamin K-dependent protein C; EC 3.4.21; OTTHUMP00000203820; OTTHUMP00000203827; Blood coagulation factor XIV; Autoprothrombin IIA; Anticoagulant protein C protein C (inactivator of coagulation factors Va and VIIIa); Activation peptide; Anticoagulant protein C; PROC_HUMAN; Protein C (inactivator of coagulation factors Va and VIIIa); THPH3; THPH4; Vitamin K dependent protein C; Protein C

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