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prkdc

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Official Full Name
protein kinase, DNA-activated, catalytic polypeptide
Background
This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010]
Synonyms
PRKDC; protein kinase, DNA-activated, catalytic polypeptide; HYRC; p350; DNAPK; DNPK1; HYRC1; XRCC7; DNA-PKcs; DNA-dependent protein kinase catalytic subunit; p460; DNA-PK catalytic subunit; hyper-radiosensitivity of murine scid mutation, complementing 1