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prkaca

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Official Full Name
protein kinase, cAMP-dependent, catalytic, alpha
Background
cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the;cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The;inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the;dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric;catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans.;The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of;cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been;observed.
Synonyms
PRKACA; protein kinase, cAMP-dependent, catalytic, alpha; cAMP-dependent protein kinase catalytic subunit alpha; PKACa; PKA C-alpha; protein kinase A catalytic subunit; cAMP-dependent protein kinase catalytic subunit alpha, isoform 1; MGC48865; MGC102831; Cs; PKA; PKCD