Creative biogene
SHARE THIS
facebook twitterlinkedingoogle plusStumbleUpon blog


Products
CBpromise

24x7 CUSTOMER SERVICE

CONTACT US TO ORDER

;

prdm16

Bookmark and Share
Official Full Name
PR domain containing 16
Background
The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Synonyms
PRDM16; PR domain containing 16; MEL1; LVNC8; PFM13; CMD1LL; PR domain zinc finger protein 16; MDS1/EVI1-like gene 1; transcription factor MEL1;

CONTACT CREATIVE BIOGENE

45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-biogene.com

Europe
Tel: 44-207-097-1828

Terms & Conditions | Privacy Policy | Sitemap | FAQ | © 2010-2018 Creative Biogene. All Rights Reserved.