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pram1

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Official Full Name
PML-RARA regulated adaptor molecule 1
Background
The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha).
Synonyms
PRAM1; PML-RARA regulated adaptor molecule 1; PML-RARA-regulated adapter molecule 1; PML RAR; PML RARA target gene encoding an Adaptor Molecule 1; PRAM; PML-RARA target gene encoding an Adaptor Molecule-1; PRAM-1; PML-RAR; MGC39864

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