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ppp2r1b

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Official Full Name
protein phosphatase 2, regulatory subunit A, beta
Background
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.
Synonyms
PPP2R1B; protein phosphatase 2, regulatory subunit A, beta; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform , protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; PP2A A beta; PP2A Abeta; PR65B; protein phosphatase 2A; regulatory subunit A; beta isoform; 2AAB_HUMAN; beta isoform of regulatory subunit A, protein phosphatase 2; PP2A subunit A isoform PR65-beta; PP2A subunit A isoform R1-beta; PP2A, subunit A, PR65 beta isoform; PP2A, subunit A, R1 beta isoform; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform; protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform; protein phosphatase 2, structural/regulatory subunit A, beta isoform; serine/threonine protein phosphatase 2A 65 kDa regulatory subunit A, beta isoform; serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, beta isoform; PP2A, subunit A, R1-beta isoform; PP2A, subunit A, PR65-beta isoform; protein phosphatase 2, structural/regulatory subunit A, beta; PP2A-Abeta; MGC26454; zgc:92493; wu:fa11a11; wu:fb38a08; ik:tdsubc_2h3; xx:tdsubc_2h3; tdsubc_2h3; protein phosphatase 2 (formerly 2A),

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