The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.
PPM1G; protein phosphatase, Mg2+/Mn2+ dependent, 1G; protein phosphatase 1G (formerly 2C), magnesium dependent, gamma isoform; protein phosphatase 1G; PP2C; gamma; PP2CG; PP2Cgamma; protein phosphatase 2C; gamma isoform; "PP2C; MGC1675; MGC2870; OTTHUMP00000123426; PP2C gamma; PP2C-gamma; PPM1G_HUMAN; PPP2CG; Protein phosphatase 1C; Protein phosphatase 2 catalytic subunit gamma isoform; Protein phosphatase 2C gamma isoform; Protein phosphatase 2C isoform gamma; Protein phosphatase magnesium dependent 1 gamma; Protein phosphatase magnesium-dependent 1 gamma; PP2C, gamma; protein phosphatase 2, catalytic subunit, gam; protein phosphatase 2, catalytic subunit, gamma isoform; protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform; cb167; wu:fb37b10; wu:fe01e01