This gene is a member of the cyclophilin family of peptidylprolyl isomerases. The cyclophilins are a highly conserved ubiquitous family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. This protein interacts with the proteinase inhibitor eglin c and is localized in the nucleus. Multiple transcript variants encoding different isoforms have been found for this gene.
PPIL2; peptidylprolyl isomerase (cyclophilin)-like 2; peptidyl-prolyl cis-trans isomerase-like 2; Cyp 60; FLJ39930; CYC4; Cyclophilin 60; Cyclophilin 60kDa; Cyclophilin like protein Cyp 60; Cyclophilin-60; Cyclophilin-like protein Cyp-60; CYP60; hCyP 60; MGC33174; MGC787; Peptidyl prolyl cis trans isomerase like 2; Peptidylprolyl cis trans isomerase; Peptidylprolyl isomerase cyclophilin like 2; PPIase; PPIL2_HUMAN; Rotamase; Rotamase PPIL2; cyclophilin, 60kDa; peptidylprolyl cis-trans isomerase; Cyp-60; hCyP-60; CYC4, CYP60, Cyp-60, FLJ39930, MGC33174, MGC787, hCyP-60, PPIL2; zgc:56616; zgc:86735; si:dkeyp-86g2.1; DKEYP-86G2.1