Official Full Name
phosphatidic acid phosphatase type 2A
The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is an integral membrane glycoprotein, and has been shown to be a surface enzyme that plays an active role in the hydrolysis and uptake of lipids from extracellular space. The expression of this gene is found to be regulated by androgen in a prostatic adenocarcinoma cell line. At least two alternatively spliced transcript variants encoding distinct isoforms have been described.
PPAP2A; phosphatidic acid phosphatase type 2A; lipid phosphate phosphohydrolase 1; LPP1; PAP 2a; Lipid phosphate phosphohydrolase 1a; LLP1a; PAP2; PAP2a2; PAP2alpha2; PAPalpha1; Phosphatidic acid phosphatase 2a; Phosphatidic acid phosphohydrolase type 2a; Type 2 phosphatidic acid phosphatase alpha; Type 2 phosphatidic acid phosphohydrolase; PAP2a; PAP2-alpha; phosphatidate phosphohydrolase type 2a; type-2 phosphatidic acid phosphatase alpha; PAP-2a; WUN