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pms2

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Official Full Name
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
Background
Microsatellite instability (MSI) is characterized by genome-wide alterations in short, repetitive DNA sequences. It is caused by defects in the nucleotide mismatch repair (MMR) system. Biologically, defective MMR results in a general increase in the mutat
Synonyms
PMS2; PMS2 postmeiotic segregation increased 2 (S. cerevisiae); PMSL2, postmeiotic segregation increased (S. cerevisiae) 2; mismatch repair endonuclease PMS2; H_DJ0042M02.9; HNPCC4; PMS1 protein homolog 2; DNA mismatch repair protein PMS2; PMSL2; PMS2CL