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plag1

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Official Full Name
pleiomorphic adenoma gene 1
Background
Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas. Three transcript variants encoding two different isoforms have been found for this gene.
Synonyms
PLAG1; pleiomorphic adenoma gene 1; zinc finger protein PLAG1; ZNF912; FGFR1/PLAG1 fusion variant 3; PLAG1_HUMAN; Pleiomorphic adenoma gene 1 protein; PSA; SGPA; OTTHUMP00000226422; OTTHUMP00000226423; OTTHUMP00000226424; COL1A2/PLAG1 fusion