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pir

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Official Full Name
pirin (iron-binding nuclear protein)
Background
This gene encodes a member of the cupin superfamily. The encoded protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described.
Synonyms
PIR; pirin (iron-binding nuclear protein); pirin; Iron binding nuclear protein; OTTHUMP00000022961; OTTHUMP00000022962; probable quercetinase; probable quercetin 2,3-dioxygenase PIR; zgc:92778

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